Category: Molecular, Cellular, and Biomedical Sciences

Resource Category Topic Type
Comparative phosphoproteomic profiling of type III adenylyl cyclase knockout and control, male, and female mice
UNH researchers are one step closer to understanding why autism is four times more common in boys than in girls after identifying and characterizing the connection of certain proteins in the brain to autism spectrum disorders.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Molecular Biology Resource
Cophylogeny and convergence shape evolution in sponge–microbe symbioses
Sponges in coral reefs are among the earliest animals on the planet. Research from UNH examines coral reef ecosystems with a novel approach to understanding the complex evolution of sponges and the microbes that live in symbiosis with them.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Ecosystem Services, Genetics and Genomics, Molecular Biology Resource
Epigenetic targeting of waldenstrom macroglobulinemia cells with BET inhibitors synergizes with BCL2 or histone deacetylase inhibition
Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment, making it challenging to treat patients. But with the work being done at UNH, that may one day change.
Molecular, Cellular, and Biomedical Sciences Molecular Biology Resource
Harnessing plant-microbiome interactions for bioremediation across a freshwater urbanization gradient
This research demonstrates how harnessing variation in plants and microbiomes could improve bioremediation (i.e., the process in which biological systems transform organic contaminants into less toxic byproducts). Researchers found that experimental microcosms with duckweeds rapidly transformed the organic contaminant benzotriazole. However, microcosms with duckweeds from rural sites, diverse microbiomes, or algae were able to bioremediate a larger amount of benzotriazole.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Ecosystem Services, Molecular Biology, Water Management Resource
Induction of activity synchronization among primed hippocampal neurons out of random dynamics is key for trace memory formation and retrieval
A team of UNH researchers found that the neurons involved in so-called Pavlovian conditioning (also known as respondent or classical conditioning) shift their behaviors during this learning procedure, becoming more synchronized when a memory is being formed. They published their study findings in an issue of the Journal of the Federation of American Societies for Experimental Biology.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Molecular Biology Resource
Limited evidence for parallel evolution among desert-adapted peromyscus deer mice
Researchers at the University of New Hampshire found that to live in hotter more desert-like surroundings, and exist without water, there is more than one genetic mechanism allowing animals to adapt.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Climate Science, Ecosystem Services, Genetics and Genomics Resource
Molecular interactions and inhibition of the SARS-CoV-2 main protease by a thiadiazolidinone derivative
In a first-of-its-kind study, UNH researchers found that using an existing drug compound in a new way, known as drug repurposing, could be successful in blocking the activity of a key enzyme of the coronavirus, or SARS-CoV-2, which causes COVID-19.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Genetics and Genomics, Molecular Biology Resource
PDE6 study with activated G protein reveals how visual excitement works through its molecular structure
UNH researchers published a paper in Journal of Biological Chemistry showing the first structural model for an enzyme involved in inherited eye diseases, offering clues for new drug development.
 Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Molecular Biology Resource
Structural analysis of the regulatory GAF domains of cGMP phosphodiesterase elucidates the allosteric communication pathway
UNH researchers have advanced our understanding of the mutations that result in color blindness and certain retinal degenerative diseases that cause blindness.
Molecular, Cellular, and Biomedical Sciences, Peer Reviewed Journal Articles Molecular Biology Resource
The genome of the softshell clam and the evolution of apoptosis
Building on a decades-long legacy of UNH research into cancer in the softshell clam (Mya arenaria), a recent paper by a team of UNH researchers sheds new light on how apoptosis evolved in invertebrates. Their research overturns a longstanding idea in the science of apoptosis by finding that the genetic repertoire that the clam uses for its apoptosis pathway is more similar to humans than to other invertebrates that have been studied.
 Molecular, Cellular, and Biomedical Sciences Genetics and Genomics Resource
UNH COVID-19 lab surpasses million test milestone
The University of New Hampshire's uniquely designed lab has completed more than one million tests to detect and monitor the coronavirus. The cutting-edge lab not only performs specifically designed self-swab tests for students, faculty and staff but also plays an important testing role to help provide a safe environment for the greater community by processing tests for more than 125 other groups, including secondary schools, long term-care facilities and other colleges in the state.
 Molecular, Cellular, and Biomedical Sciences Genetics and Genomics Resource
UNH receives NIH grant to continue genomic surveillance of COVID-19 variants in New Hampshire
UNH awarded NIH funding to study COVID-19 variants in New Hampshire through genomic surveillance. The aim is to comprehend variant's impact on transmission, immunity evasion & symptom severity.
 Funded Proposals, Molecular, Cellular, and Biomedical Sciences Genetics and Genomics, Molecular Biology Resource