Vicki Jeffers

ASSISTANT PROFESSOR
Phone: (603) 862-2103
Office: UNH Molecular, Cellular, & Biomedical Sciences, Rudman Hall, Durham, NH 03824
Vicki Jeffers

Research Interests

  • Antimicrobials
  • Cellular Biology
  • Drug Discovery
  • Epigenetics
  • Gene Expression
  • Gene Regulation
  • Genetic Manipulation
  • Infectious Diseases/Agents
  • Microbes
  • Microbiology
  • Molecular Biology
  • Parasitology
  • Pathogenesis
  • Transcription

Courses Taught

  • INCO 590: Rsrch Exp/MCBS

Selected Publications

Harris, M. T., Jeffers, V., Martynowicz, J., True, J. D., Mosley, A. L., & Sullivan, W. J. (2019). A novel GCN5b lysine acetyltransferase complex associates with distinct transcription factors in the protozoan parasite Toxoplasma gondii. Molecular and Biochemical Parasitology, 232, 111203. doi:10.1016/j.molbiopara.2019.111203

Jeffers, V., Tampaki, Z., Kim, K., & Sullivan, W. J. (2018). A latent ability to persist: differentiation in Toxoplasma gondii. Cellular and Molecular Life Sciences, 75(13), 2355-2373. doi:10.1007/s00018-018-2808-x

Jeffers, V., Yang, C., Huang, S., & Sullivan, W. J. (2017). Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development. Microbiology and Molecular Biology Reviews, 81(1). doi:10.1128/mmbr.00047-16

Jeffers, V., Kamau, E. T., Srinivasan, A. R., Harper, J., Sankaran, P., Post, S. E., . . . Boyle, J. P. (2017). TgPRELID, a Mitochondrial Protein Linked to Multidrug Resistance in the Parasite
Toxoplasma gondii. mSphere, 2(1). doi:10.1128/msphere.00229-16

Jeffers, V., Gao, H., Checkley, L. A., Liu, Y., Ferdig, M. T., & Sullivan, W. J. (2016). Garcinol Inhibits GCN5-Mediated Lysine Acetyltransferase Activity and Prevents Replication of the Parasite Toxoplasma gondii. Antimicrobial Agents and Chemotherapy, 60(4), 2164-2170. doi:10.1128/aac.03059-15

Miao, J., Lawrence, M., Jeffers, V., Zhao, F., Parker, D., Ge, Y., . . . Cui, L. (2013). Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions duringPlasmodium falciparumintraerythrocytic development. Molecular Microbiology, 89(4), 660-675. doi:10.1111/mmi.12303

Xue, B., Jeffers, V., Sullivan, W. J., & Uversky, V. N. (2013). Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii. Molecular BioSystems, 9(4), 645. doi:10.1039/c3mb25517d

Jeffers, V., & Sullivan, W. J. (2012). Lysine Acetylation Is Widespread on Proteins of Diverse Function and Localization in the Protozoan Parasite Toxoplasma gondii. Eukaryotic Cell, 11(6), 735-742. doi:10.1128/ec.00088-12

Sullivan, W. J., & Jeffers, V. (2012). Mechanisms ofToxoplasma gondiipersistence and latency. FEMS Microbiology Reviews, 36(3), 717-733. doi:10.1111/j.1574-6976.2011.00305.x

Wang, J., Dixon, S. E., Ting, L. -M., Liu, T. -K., Jeffers, V., Croken, M. M., . . . Sullivan, W. J. (n.d.). Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation. PLoS Pathogens, 10(1), e1003830. doi:10.1371/journal.ppat.1003830

Most Cited Publications