Don Wojchowski

PROFESSOR
Phone: (603) 862-1497
Office: Molecular, Cellular, & Biomedical Sciences, Rudman Hall Rm 279, Durham, NH 03824
Don

Scientifically, my expertise lies in the areas of cytokine actions; erythropoiesis & hematopoiesis; and progenitor cell biology. To date, ~80 major publications have been contributed; independent NIH funding has been in-place since 1987; and ~35 scientists have been trained and placed. Administratively, I previously directed Penn State’s Immunobiology Program. While at the Maine Medical Center Research Institute, I served as Director of the COBRE Center of Excellence in Stem & Progenitor Cell Biology and Regenerative Medicine (2005-2017) and as a member of the Internal Steering Committee for MMCRI’s Phase-III COBRE in Vascular Biology. Nationally, I serve frequently on NIH special emphasis and Center review panels, contribute to workshops, and have served as a full-member of NIH’s Study Section in Molecular and Cellular Hematology (and previously, as a regular member of HEM2 Study Section). I also review frequently for Nature Medicine, Science, Blood, NEJM, Experimental Hematology, and have worked in sponsored and collaborative programs with a number of biopharma entities (eg, GSK, Centocor, Amgen, Affymax, RW Johnson, Adeptrix, Cell Signaling Technology).

Education

  • Ph.D., Zoology/Animal Biology, University of Massachusetts - Amherst
  • B.A., Colby College

Research Interests

  • Anemia
  • Bioinformatics
  • Blood Diseases
  • Cell Death
  • Cell Lines
  • Cellular Biology
  • Disease Model
  • Drug Discovery
  • Gene Expression
  • Gene Regulation
  • Genomics
  • Hybridomas
  • Inhibitors
  • Kidney Disease
  • Leukemia
  • Mass Spectrometry
  • Proteomics
  • Receptors
  • Sickle Cell Disease
  • Signal Transduction (Sensory/Cellular)

Courses Taught

  • BENG 620: Tissue Engineering
  • BMS 620: Tissue Eng Cell Culture Lab
  • INCO 590: Rsrch Exp/MCBS
  • INCO 790: Adv Rsrch Exp/MCBS
  • MCBS 905: Contemp Top Molec/Cell/Biomed
  • MCBS 997: Seminar

Selected Publications

Wojchowski, D. M. (2018). Ineffective erythropoiesis of TET2 deficiency. BLOOD, 132(22), 2320-2321. doi:10.1182/blood-2018-10-878645

Li, P., Karaczyn, A. A., McGlauflin, R., Favreau-Lessard, A. J., Jachimowicz, E., Vary, C. P., . . . Sathyanarayana, P. (2017). Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration. Experimental Hematology, 50, 77-83.e6. doi:10.1016/j.exphem.2017.04.001

Dev, A., Asch, R., Jachimowicz, E., Rainville, N., Johnson, A., Greenfest-Allen, E., & Wojchowski, D. M. (2017). Governing roles for Trib3 pseudokinase during stress erythropoiesis. Experimental Hematology, 49, 48-55.e5. doi:10.1016/j.exphem.2016.12.010

Verma, R., Green, J. M., Schatz, P. J., & Wojchowski, D. M. (2016). A dimeric peptide with erythropoiesis-stimulating activity uniquely affects erythropoietin receptor ligation and cell surface expression. Experimental Hematology, 44(8), 765-769.e1. doi:10.1016/j.exphem.2016.04.015

Rainville, N., Jachimowicz, E., & Wojchowski, D. M. (2016). Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis. Expert Opinion on Therapeutic Targets, 20(3), 287-301. doi:10.1517/14728222.2016.1090975

Wojchowski, D. M., Gregory, R. C., Miller, C. P., Pandit, A. K., & Pircher, T. J. (1999). Signal Transduction in the Erythropoietin Receptor System. Experimental Cell Research, 253(1), 143-156. doi:10.1006/excr.1999.4673

Gregory, R. C., Taxman, D. J., Seshasayee, D., Kensinger, M. H., Bieker, J. J., & Wojchowski, D. M. (1996). Functional interaction of GATA1 with erythroid Kruppel-like factor and SP1 at defined erythroid promoters. BLOOD, 87(5), 1793-1801. Retrieved from http://gateway.webofknowledge.com/

ZHUANG, H. M., PATEL, S. V., HE, T. C., SONSTEBY, S. K., NIU, Z. T., & WOJCHOWSKI, D. M. (1994). INHIBITION OF ERYTHROPOIETIN-INDUCED MITOGENESIS BY A KINASE-DEFICIENT FORM OF JAK2. JOURNAL OF BIOLOGICAL CHEMISTRY, 269(34), 21411-21414. Retrieved from http://gateway.webofknowledge.com/

Quelle, D. E., & Wojchowski, D. M. (1991). Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor.. Proceedings of the National Academy of Sciences, 88(11), 4801-4805. doi:10.1073/pnas.88.11.4801

QUELLE, F. W., & WOJCHOWSKI, D. M. (1991). PROLIFERATIVE ACTION OF ERYTHROPOIETIN IS ASSOCIATED WITH RAPID PROTEIN TYROSINE PHOSPHORYLATION IN RESPONSIVE B6SUT.EP CELLS. JOURNAL OF BIOLOGICAL CHEMISTRY, 266(1), 609-614. Retrieved from http://gateway.webofknowledge.com/

Most Cited Publications