David Needle

Senior Veterinary Pathologist and Clinical Assistant Professor
Phone: (603) 862-0057
Office: Molecular, Cellular, & Biomedical Sciences, Veterinary Diagnostic Lab, Durham, NH 03824

I received a DVM from the Cummings School of Veterinary Medicine at Tufts University in 2011, after which I completed a residency in Veterinary Anatomic Pathology at the Diagnostic Center for Population and Animal Health at Michigan State University.

I joined the New Hampshire Veterinary Diagnostic Laboratory and UNH in 2015. My work since consists predominantly of diagnostic pathology serving primary care veterinarians as well as livestock producers, zoological collections, and wildlife agencies. The latter, combined with collaboration with colleagues at UNH and afield has led to the development of nascent research in emerging and zoonotic wildlife disease surveillance in the broader context of One Health.


  • D.V.M., Tufts University
  • B.A., Tufts University

Research Interests

  • Animal Diseases/Pathology
  • Emerging Diseases
  • Infectious Diseases/Agents
  • Veterinary Medicine
  • Wildlife
  • Zoonotic Diseases

Courses Taught

  • BMS 600: Field Experience
  • BMS 623: Histology
  • BMS 704: Pathologic Basis of Disease
  • BMS 712: Grand Rounds
  • BMS 795W: Investigations Biomedical Sci
  • BMS 799H: Senior Honors Thesis
  • INCO 790: Adv Rsrch Exp/MCBS

Selected Publications

Barth, B. M., Wang, W., Toran, P. T., Fox, T. E., Annageldiyev, C., Ondrasik, R. M., . . . Claxton, D. F. (2019). Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia. Blood Advances, 3(17), 2598-2603. doi:10.1182/bloodadvances.2018021295

Needle, D. B., Burnell, V. C., Forzán, M. J., Dubovi, E. J., Schuler, K. L., Bernier, C., . . . Wilkes, R. P. (2019). Infection of eight mesocarnivores in New Hampshire and Vermont with a distinct clade of canine distemper virus in 2016–2017. Journal of Veterinary Diagnostic Investigation, 31(4), 562-567. doi:10.1177/1040638719847510

Needle, D. B., Selig, M. K., Jackson, K. A., Delwart, E., Tighe, E., Leib, S. L., . . . Pesavento, P. A. (2019). Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. Journal of Veterinary Diagnostic Investigation, 31(1), 103-106. doi:10.1177/1040638718812123

Needle, D. B., Iglikova, O., & Miller, A. D. (2018). Biphasic malignant melanoma adenocarcinoma in the digit of a dog. Journal of Veterinary Diagnostic Investigation, 30(2), 315-318. doi:10.1177/1040638717752424

Christman, J. E., Needle, D. B., & Williams, K. J. (2017). Pathology in Practice. Journal of the American Veterinary Medical Association, 251(4), 405-407. doi:10.2460/javma.251.4.405

A.M., A. H., J.A., G., C.L., L., S., O., S., N., D.B., N., . . . C.M., W. (2017). A bioluminescent Pseudomonas aeruginosa wound model reveals increased mortality of type 1 diabetic mice to biofilm infection. Journal of Wound Care, 26(Sup7), S24-S33. doi:10.12968/jowc.2017.26.sup7.s24

Sloup, R. E., Cieza, R. J., Needle, D. B., Abramovitch, R. B., Torres, A. G., & Waters, C. M. (2016). Polysorbates prevent biofilm formation and pathogenesis ofEscherichia coliO104:H4. Biofouling, 32(9), 1131-1140. doi:10.1080/08927014.2016.1230849

Johnson, B. K., Colvin, C. J., Needle, D. B., Mba Medie, F., Champion, P. A. D., & Abramovitch, R. B. (2015). The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrobial Agents and Chemotherapy, 59(8), 4436-4445. doi:10.1128/aac.00719-15

Pumphrey, S. A., Pizzirani, S., Pirie, C. G., & Needle, D. B. (2013). Glaucoma associated with uveal cysts and goniodysgenesis in American Bulldogs: a case series. Veterinary Ophthalmology, 16(5), 377-385. doi:10.1111/vop.12000

Needle, D., McKnight, C. A., & Kiupel, M. (2013). Chondroblastic Osteosarcoma in Two Related Spiny-Tailed Monitor Lizards (Varanus acanthurus). Journal of Exotic Pet Medicine, 22(3), 265-269. doi:10.1053/j.jepm.2013.08.013

Most Cited Publications