David Needle, D.V.M, Dipl. ACVP

David Needle, D.V.M, Dipl. ACVP

Clinical Assistant Professor, Senior Veterinary Pathologist

Educational Background:

Post-doctoral fellowship, Abramovitch Laboratory, Michigan State University, 2014-2015
Residency in Anatomic Pathology, Diagnostic Center for Population and Animal Health, Michigan State University, 2011-2014
DVM, Tufts University Cummings School of Veterinary Medicine, 2007-2011
BA, Tufts University, 1999-2003

Courses Taught:

BMS 704 - Pathologic Basis of Disease
BMS 712 – Grand Rounds

General Area of Interest and/or Specialty:

Diagnostic pathology, emerging infectious diseases, comparative pathology, microbial pathogenesis

Description of Current Research and/or Professional Activities:

The majority of my work is as a diagnostic pathologist at the NHVDL, where the biopsy and necropsy service includes specimens from domesticated animals, wildlife, zoo animals, and laboratory animals. Being a diagnostic pathologist, my interests are broad and my research projects are dictated by the varied caseload at the NHVDL. The projects that I find most exciting involve novel diseases or lesions that I encounter in my clinical work. This interest in combination with the NHVDL’s strong presence in domestic and regional wildlife and zoological pathology has resulted in a particular interest in emerging infectious diseases in animals. I also enjoy the opportunity to collaborate with principle investigators that use animal models of disease.


Thompson KA, Patterson J, Fitzgerald SD, Needle D, Harrison T. TREATMENT OF RENAL CARCINOMA IN A BINTURONG (ARCTICTIS BINTURONG) WITH NEPHRECTOMY AND A TYROSINE KINASE INHIBITOR. J Zoo Wildl Med. 2016 Dec;47(4):1109-1113. doi: 10.1638/2015-0285.1.

Sloup RE, Cieza RJ, Needle DB, Abramovitch RB, Torres AG, Waters CM. Polysorbates prevent biofilm formation and pathogenesis of Escherichia coli O104:H4. Biofouling. 2016 Oct;32(9):1131-1140.

Needle DB, Hollinger C, Singer LM, Kiupel M, Swenson C, Mullaney TP. Pathology in Practice. Lymphomatoid granulomatosis of lung tissue and mediastinal lymph node in a dog. J Am Vet Med Assoc. Nov 15, 2015;247(10):1113-6    

Johnson BK, Colvin CJ, Needle DB, Mba Medie F, Champion PA, Abramovitch RB. The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrob Agents Chemother. 2015 Aug;59(8):4436-45

Zoll W, Needle DB, French SJ, Lim A, Bolin S, Langhor I, Agnew D. Sarcocystis spp infection in two Red Panda Cubs (Ailurus fulgens). J Comp Pathol. Aug-Oct 2015;153(2-3):185-9

Needle DB, Hollinger C, Shelton GD, Fitzgerald SD. Necrotizing and Eosinophilic Masticatory Myositis in Farmed Mink: a Preliminary Description, J Comp Pathol 2014 Aug-Oct;151(2-3):217-27

Needle DB, Mietelka KA.  Pathology in practice - Juvenile Canine Parvovirus Cardiomyositis in Three Littermates.  J Am Vet Med Assoc. May 15, 2014;244(10):1155-7

Kohnken R, Needle DB, French SJ, Patterson JS. What is your diagnosis - Gallibacterium anatis in an Adult Brahma Chicken. J Avian Med and Surg. 2014;28(4):343-7

Needle DB, McKnight C, Kiupel M.  Chondroblastic Osteosarcoma in Two Related Spiny-Tailed Monitor Lizards (Varanus Acanthurus). J Exotic Pet Med. 2013:22(3);265-269

Pumphrey SA, Pizzirani S, Pirie CG, Needle DB. Glaucoma associated with uveal cysts and goniodysgenesis in American Bulldogs: a case series. Vet Ophthalmol. Sep 2013;16(5):377-85

Needle DB, Krien S, Sharp CR. Pathology in practice - Left subclavian arterial thromboembolism and perirenal hemangiosarcoma in a dog.  J Am Vet Med Assoc.  April 1, 2013;242(7);931-933

Christman J, Needle DB, Williams KJ. Systemic Bibersteiniosis in a ewe lamb. Accepted 6/10/2015 to J Am Vet Med Assoc.

21 Botanical Lane, Room 107
Durham, NH 03824
(603) 862-2726